Survey of multi-drug resistant bacteria responsible for chronic urinary tract infections in Al Mahalla regional cities in Egypt

Khedr, Mohamed; Abdallah, Ahmed; Abdelmouty, Eslam S; Emam, Ahmed N.; Ewais, Emad A

doi:10.21608/ajar.2024.302959.1369

Survey of multi-drug resistant bacteria responsible for chronic urinary tract infections in Al Mahalla regional cities in Egypt

Document Type : Original Article

Authors

¹ قسم النبات والميكروبيولوجي, كلية العلوم جامعة الازهر -مدينة نصر- القاهرة- مصر

² قسم النبات والميكروبيولوجي كلية العلوم جامعة الازهر

³ المركز القومي للبحوث

10.21608/ajar.2024.302959.1369

Abstract

Among chronic bacterial infections in humans is Urinary tract infection particularly when these infections are caused through Multi drug resistant (MDR) isolates which resist various traditional treatment especially antibiotic-based methods. In this article we were isolate then biochemical and molecular identification of most potent MDR isolates cause Urinary tract infection (UTIs) in Egyptian patients’ males and females. So, in our study we obtained 22 different bacterial isolates which all are gram negative belonging to different four genera based on their growth on Uriselect into E. coli, Klebsiella sp, Pseudomonas sp., and Acinetobacter sp., they have beta-hemolytic activity, beside that they exhibit MDR behavior against twelve antibiotics, according to growth on Macconkey agar, 17 isolates with lactose fermenting (16 Klebsiella sp and one E. coli) and five were non-lactose fermenting isolates. The most potent bacterial isolates were Klebsiella pneumonia A061 and Klebsiella pneumonia A031 with accession numbers OP811040 and OP811041 respectively. Finally, among MDR bacterial isolates, Klebsiella pneumonia is one of the most threat of Urinary tract infection in Egyptian people as they resist traditional treatment with antibiotics.

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